Fibrous Dysplasia
Fibrous dysplasia is a chronic disorder of the skeleton that causes expansion of one or more bones due to abnormal development of the fibrous, or connective, tissue within the bone. The abnormality will cause uneven growth, brittleness and deformity in affected bones. Some patients have only one bone affected (monostotic), whereas other patients have numerous bones affected (polyostotic). While any bone can be affected by fibrous dysplasia, the most common sites of the disease are the femur (thigh bone), tibia (shin bone), ribs, skull, facial bones, humerus (upper arm), and pelvis. The vertebrae are less frequently involved. Although many bones can be affected at once, fibrous dysplasia is not a disease that spreads from one bone to another. Multiple affected bones are often found on one side of the body.
Who is Affected
Fibrous dysplasia is a very uncommon disorder, and the total number of cases is not known. It is usually diagnosed in children and young adults. If the disease involves more than one bone, it is more likely to produce problems before age 10. The disease is found equally in males and females and does not appear to vary in incidence among races.

Content Courtesy : www.osteo.org
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