Preventive Mastectomy, Prophylactic Mastectomy
Preventive mastectomy (also called prophylactic mastectomy) is the surgical removal of one or both breasts in an effort to prevent or reduce the risk of breast cancer. Total mastectomy, an operation to remove the entire breast and nipple, is the procedure of choice. Subcutaneous mastectomy, an operation to remove the breast tissue but spare the nipple, is recommended less often because of the possibility of leaving cancerous breast tissue behind. It is important that a woman who is considering preventive mastectomy talk with a doctor about her risk of developing breast cancer (with or without a mastectomy), the surgical procedure, and potential complications. She should also discuss her feelings about mastectomy, alternatives to surgery, and followup care. A woman may also wish to get a second medical opinion to help with the decision.

Reasons for Preventive Mastectomy
Preventive mastectomy may be considered for several reasons. Women who have already had one breast removed due to cancer may consider this procedure in an effort to avoid developing a new cancer in the other breast. Preventive mastectomy may also be an option for women with a strong family history of breast cancer, especially if several close relatives developed the disease before age 50. Women in families with hereditary breast cancer who test positive for a known cancer-causing gene alteration may also consider this surgery. In addition, preventive mastectomy is sometimes considered for women who have had lobular carcinoma in situ, a condition that increases their risk of developing breast cancer in the same and/or in the opposite breast. Rarely, preventive mastectomy may be considered for women with diffuse and indeterminate breast microcalcifications (tiny deposits of calcium in the breast) or for women whose breast tissue is very dense. (This is particularly important in women who have already had a mastectomy in the other breast.) Dense breast tissue is linked to an elevated risk of breast cancer and also makes diagnosing breast abnormalities difficult. Multiple biopsies, which may be necessary for diagnosing abnormalities in dense breasts, cause scarring and further complicate examination of the breast tissue.
Although having a preventive mastectomy can reduce the risk, no one can be certain that this procedure will protect a woman from breast cancer. Because it is impossible for a surgeon to remove all breast tissue, breast cancer can still develop in the small amount of remaining tissue. All women are different, so the procedure should be considered in the context of each woman's unique risk factors and her level of concern.
Content Courtesy : cis.nci.nih.gov
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