Synovial Sarcoma
Synovial sarcoma is a rare cancer that begins in synovial tissue. Synovial tissue is found in tendons (tissues that connect muscle to bone), bursae (fluid-filled, cushioning sacs in the spaces between tendons, ligaments, and bones), and the hollow area that separates the bones of a joint, such as the knee or elbow.

Synovial sarcomas occur mainly in the legs and arms, where they tend to arise near large joints, especially around the knee. Less frequently, the disease develops in the head and neck and in the trunk. This cancer occurs mostly in older adolescents and young adults, and it affects slightly more men than women. Researchers do not know what causes synovial sarcoma.

The most common symptom of synovial sarcoma is a deep-seated swelling or a mass that may be tender or painful. In a few cases, a person may have tenderness or pain for several years, even though a mass cannot be felt. These cases can be easily mistaken for inflammation of the joints, the bursae, or synovial tissue (these noncancerous conditions are called arthritis, bursitis, and synovitis). Sometimes synovial sarcoma causes other symptoms related to the location of the tumor. The diagnosis of synovial sarcoma is made by biopsy (removal of tissue for examination under a microscope).

Content Courtesy : cis.nci.nih.gov
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