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Treatment for Pulmonary Hypertension
There is currently no standard
therapy for the treatment of
pulmonary hypertension associated
with CHD. There have been several
small studies using intravenous
epoprostenol (FlolanĘ), but their
small size make it difficult to
determine any effects on long-term
survival. Studies using similar
therapies to Flolan, such as UT15
(subcutaneous prostacyclin), inhaled
prostacyclin, and Beraprost (oral
prostacyclin) have included patients
with CHD, but the data are too
preliminary to derive any meaningful
conclusions at this time.
There are several active drug trials
for primary pulmonary hypertension
which appear to be promising (i.e.
Bosentan/TracleerĘ), but it will be
some time before patients with CHD
are included in these studies.
Patients with congenital heart
disease and pulmonary hypertension
are not included early in these
studies because of their very
different symptomatology and
survival pattern.
Chronic anticoagulation (blood
thinning to inhibit clotting)
therapy is standard for patients
with primary pulmonary hypertension.
This kind of therapy is used because
clotting within the lungs is thought
to make the progression of the
disease more rapid. Many clinicians
recommend anticoagulation to
patients with pulmonary hypertension
and CHD even though the long-term
effects of such therapy such have
not been studied.
As with all causes of pulmonary
hypertension, all other contributing
"triggers" should be treated. For
example, if low oxygen levels
respond to supplemental oxygen,
continuous oxygen inhalation is
recommended.
Content Courtesy : www.achaheart.org
The information provided herein
is intended for your general
knowledge only and is not a
substitute for medical advice or
treatment for specific medical
conditions. The information should
not be used during any medical
emergency or for the diagnosis or
treatment of any medical condition.
A licensed physician should be
consulted for diagnosis and
treatment of any and all medical
conditions.
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